You are currently browsing the Anti-Aging Firewalls weblog archives for the day 26. July 2009.
| M | T | W | T | F | S | S |
|---|---|---|---|---|---|---|
| « Jun | Aug » | |||||
| 1 | 2 | 3 | 4 | 5 | ||
| 6 | 7 | 8 | 9 | 10 | 11 | 12 |
| 13 | 14 | 15 | 16 | 17 | 18 | 19 |
| 20 | 21 | 22 | 23 | 24 | 25 | 26 |
| 27 | 28 | 29 | 30 | 31 | ||
- Admin (1)
- Blogroll (1)
- Uncategorized (252)
- Weekly Posts (2)
- 11. March 2010: The social cost of Alzheimer’s disease and late-life dementia
- 9. March 2010: Vitamin D3 and the immune response
- 7. March 2010: Sestrins, longevity and cancers
- 3. March 2010: BDNF gene – personality, mental balance, dementia, aging and epigenomic imprinting
- 1. March 2010: DNA repair cleanup failure – a root cause for cancers?
- 27. February 2010: Joy and sadness of aging – and the impacts of longevity
- 25. February 2010: New views of Alzheimer’s disease and new approaches to treating it
- 22. February 2010: IPSCs, telomerase, and closing the loop in the stem cell supply chain
- 21. February 2010: Genome-wide association studies
- 18. February 2010: “I have never seen a doctor”
Archive for 26. July 2009
Research evidence for the Decline In Adult Stem Cell Differentiation theory of aging.
26. July 2009 by admin.
A study published in the latest issue of the online journal Cell Stem Cell provides additional research evidence supporting the Decline in Adult Stem Cell Differentiation theory of aging, the 14th theory treated in my treatise. This theory holds that aging is due to a slowing rate of organ regeneration due to declining somatic cell differentiation activity. This theory states that in addition to or perhaps instead of being concerned that aging is due to cells being damaged or reaching their reproductive limit (such as according to the Oxidative Damage or the Telomere Shortening and Damage theories of aging), we should be concerned that cells are not being replaced by freshly minted cells created by differentiating stem cells.
The new study report TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance indicates that “that the p53 family member, TAp63, is essential for maintenance of epidermal and dermal precursors and that, in its absence, these precursors senesce and skin ages prematurely.” “TAp63
Again the message is that if you are worried about aging, be concerned with the supply chain for new somatic cells. Start focusing on what is happening to adult stem cells.
Posted in Uncategorized | 1 Comment »