Comments on: Trojan-horse stem cells might offer an important new cancer therapy http://anti-agingfirewalls.com/2009/05/20/trojan-horse-stem-cells-might-offer-an-important-new-cancer-therapy/ A weblog on the science and practices of living healthily very long - perhaps hundreds of years. Thu, 09 Sep 2010 09:56:39 +0000 http://wordpress.org/?v=2.2.1 By: admin http://anti-agingfirewalls.com/2009/05/20/trojan-horse-stem-cells-might-offer-an-important-new-cancer-therapy/#comment-1338 admin Thu, 21 May 2009 18:58:37 +0000 http://anti-agingfirewalls.com/2009/05/20/trojan-horse-stem-cells-might-offer-an-important-new-cancer-therapy/#comment-1338 What a good question. It appears that curcumin, resveratrol and perhaps many of the other phyto-substances in the anti-cancer firewall work through the same mechanism as the TRAIL-loaded stem cells do. They induce differential apoptosis in cancer cells via TRAIL working on death receptors 4 and 5. See http://books.google.com/books?id=NP8JZOF5JtUC&pg=PA141&lpg=PA141&dq=resveratrol+TRAIL&source=bl&ots=mLIgIUrau4&sig=NVjca7ym8lcZBJ2tdXbphnqvbnM&hl=en&ei=RKEVSvP5MpSS9QTysZDHAg&sa=X&oi=book_result&ct=result&resnum=1 and http://carcin.oxfordjournals.org/cgi/content/full/27/10/2008 In other words, taking these substances initiates the same death-creating biomolecular chain in cancer cells that the TRAIL-loaded stem cells do. As to your direct question about signaling, I don't know the answer but would like to. What a good question. It appears that curcumin, resveratrol and perhaps many of the other phyto-substances in the anti-cancer firewall work through the same mechanism as the TRAIL-loaded stem cells do. They induce differential apoptosis in cancer cells via TRAIL working on death receptors 4 and 5. See http://books.google.com/books?id=NP8JZOF5JtUC&pg=PA141&lpg=PA141&dq=resveratrol+TRAIL&source=bl&ots=mLIgIUrau4&sig=NVjca7ym8lcZBJ2tdXbphnqvbnM&hl=en&ei=RKEVSvP5MpSS9QTysZDHAg&sa=X&oi=book_result&ct=result&resnum=1 and http://carcin.oxfordjournals.org/cgi/content/full/27/10/2008
In other words, taking these substances initiates the same death-creating biomolecular chain in cancer cells that the TRAIL-loaded stem cells do.

As to your direct question about signaling, I don’t know the answer but would like to.

]]> By: Res http://anti-agingfirewalls.com/2009/05/20/trojan-horse-stem-cells-might-offer-an-important-new-cancer-therapy/#comment-1312 Res Wed, 20 May 2009 19:40:36 +0000 http://anti-agingfirewalls.com/2009/05/20/trojan-horse-stem-cells-might-offer-an-important-new-cancer-therapy/#comment-1312 interesting new methodology. / conjecture that this is because cancers excrete signaling molecules that cause the circulating MSCs to home in on them, a strategy cancers use to achieve rapid growth(ref). / Does any of the firewall substance blocks the molecule signaling? Thanks Vince as always interesting new methodology.

/ conjecture that this is because cancers excrete signaling molecules that cause the circulating MSCs to home in on them, a strategy cancers use to achieve rapid growth(ref). /

Does any of the firewall substance blocks the molecule signaling?

Thanks Vince as always

]]>