Archive for 26. February 2009

Protein origami and aging

If I were to add a 15th theory of aging to this Anti-Aging Firewalls treatise, it would possibly be Misfoldings of proteins.  The basic notion is that stress often leads to the misfolding of proteins, a process that can accelerate with age creating vulnerability to a number of disease and dysfunctional conditions.  Misfolded proteins cannot perform their intended functions, can create active mischief and probably contribute to aging in multiple ways.  This is a relatively new and complex area of molecular biology that is to a large extent still unexplored.  I have posted a long and rather technical note on the subject here in my Antiaging Firewalls Treatise.

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